Literaturnachweis - Detailanzeige
| Autor/inn/en | Erickson, Laura C.; Scott-Van Zeeland, Ashley A.; Hamilton, Gavin; Lincoln, Alan; Golomb, Beatrice A. |
|---|---|
| Titel | Brief Report: Approaches to [Superscript 31]P-MRS in Awake, Non-Sedated Children with and without Autism Spectrum Disorder |
| Quelle | In: Journal of Autism and Developmental Disorders, 42 (2012) 6, S.1120-1126 (7 Seiten)
PDF als Volltext |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 0162-3257 |
| DOI | 10.1007/s10803-011-1359-x |
| Schlagwörter | Autism; Brain; Pervasive Developmental Disorders; Spectroscopy; Children; Adolescents; Comparative Analysis; Control Groups; Parent Attitudes; Emotional Response; Diagnostic Tests |
| Abstract | We piloted a suite of approaches aimed to facilitate a successful series of up to four brain and muscle [superscript 31]Phosphorus-Magnetic Resonance Spectroscopy ([superscript 31]P-MRS) scans performed in one session in 12 "awake", non-sedated subjects (ages 6-18), 6 with autism spectrum disorders (ASD) and 6 controls. We targeted advanced preparation, parental input, physical comfort, short scan protocols, allocation of extra time, and subject emotional support. 100% of subjects completed at least one brain scan and one leg muscle scan: 42 of 46 attempted scans were completed (91%), with failures dominated by exercise muscle scans (completed in 6/6 controls but 3/6 cases). One completed scan lacked usable data unrelated to subject/scan procedure (orthodonture affected a frontal brain scan). As a group, these methods provide a foundation for conduct and enhancement of future MR studies in pediatric subjects with ASD. (As Provided). |
| Anmerkungen | Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2017/4/10 |
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