Literaturnachweis - Detailanzeige
| Autor/inn/en | Childs-Disney, Jessica L.; Kauffmann, Andrew D.; Poplawski, Shane G.; Lysiak, Daniel R.; Stewart, Robert J.; Arcadi, Jane K.; Dinan, Frank J. |
|---|---|
| Titel | A Metabolic Murder Mystery: A Case-Based Experiment for the Undergraduate Biochemistry Laboratory |
| Quelle | In: Journal of Chemical Education, 87 (2010) 10, S.1110-1112 (3 Seiten)Infoseite zur Zeitschrift
PDF als Volltext |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 0021-9584 |
| DOI | 10.1021/ed100243x |
| Schlagwörter | Biochemistry; College Science; Undergraduate Students; Science Instruction; Laboratory Experiments; Science Experiments; Genetic Disorders; Metabolism; Diseases; Case Method (Teaching Technique) |
| Abstract | In 1990, a woman was wrongly convicted of poisoning her infant son and was sentenced to life in prison. Her conviction was based on laboratory work that wrongly identified ethylene glycol as present in her son's blood and in the formula he drank prior to his death. The actual cause of the infant's death, a metabolic disease, was eventually disclosed as a result of analytical work done by scientists who believed the mother was wrongly convicted. On the basis of the scientists' work, the conviction was overturned. This real-life case serves as the launching point for a biochemistry laboratory experiment, which uses polymerase chain reaction. Students design their own primers, amplify two biological samples, and analyze the results by gel electrophoresis to determine if their patient has a genetic mutation. This genetic mutation causes the metabolic disease, which if present can be used to "solve" the case. (Contains 1 table and 1 figure.) (As Provided). |
| Anmerkungen | Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2017/4/10 |
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