[alpha]-Oxocarboxylic Acids

Autor/inn/en	Kerber, Robert C.; Fernando, Marian S.
Titel	[alpha]-Oxocarboxylic Acids
Quelle	In: Journal of Chemical Education, 87 (2010) 10, S.1079-1084 (6 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9584
DOI	10.1021/ed1003096
Schlagwörter	Chemistry; Organic Chemistry; Biochemistry; Metabolism + Suchen Sie Ihr Suchwort? Chemie; Organische Chemie; Biochemie; Stoffwechsel
Abstract	Several [alpha]-oxocarboxylic acids play key roles in metabolism in plants and animals. However, there are inconsistencies between the structures as commonly portrayed and the reported acid ionization constants, which result because the acids are predominantly hydrated in aqueous solution; that is, the predominant form is RC(OH)[subscript 2]COOH rather than the nominal RCOCOOH. We urge that this structure be more accurately reflected in tabulations by use of appropriate nomenclature and clear explanation. The combination of hydration and acid-base equilibria in these compounds provides good material for teaching and testing these concepts. After reviewing the facts on these equilibria, we provide several related problems for use in general or organic chemistry courses in the supporting information. (Contains 1 note, 2 tables and 1 scheme.) (As Provided).
Anmerkungen	Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10