Individual Differences in Spatial Pattern Separation Performance Associated with Healthy Aging in Humans

Autor/inn/en	Stark, Shauna M.; Yassa, Michael A.; Stark, Craig E. L.
Titel	Individual Differences in Spatial Pattern Separation Performance Associated with Healthy Aging in Humans
Quelle	In: Learning & Memory, 17 (2010) 6, S.284-288 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.1768110
Schlagwörter	Animals; Standardized Tests; Older Adults; Program Effectiveness; Recall (Psychology); Language Patterns; Word Recognition; Learning Processes + Suchen Sie Ihr Suchwort? Animal; Tier; Tiere; Standadised tests; Standardisierter Test; Älterer Erwachsener; Abberufung; Sprachmodell; Sprachstruktur; Worterkennung; Learning process; Lernprozess
Abstract	Rodent studies have suggested that "pattern separation," the ability to distinguish among similar experiences, is diminished in a subset of aged rats. We extended these findings to the human using a task designed to assess spatial pattern separation behavior (determining at time of test whether pairs of pictures shown during the study were in the same spatial locations). Using a standardized test of word recall to divide healthy aged adults into impaired and unimpaired groups relative to young performance, we demonstrate that aged impaired adults are biased away from pattern separation and toward pattern completion, consistent with the rodent studies. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10