Successful Aging in a 70-Year-Old Man with Down Syndrome: A Case Study

Autor/inn/en	Krinsky-McHale, Sharon J.; Devenny, Darlynne A.; Gu, Hong; Jenkins, Edmund C.; Kittler, Phyllis; Murty, Vundavalli V.; Schupf, Nicole; Scotto, Luigi; Tycko, Benjamin; Urv, Tiina K.; Ye, Lingling; Zigman, Warren B.; Silverman, Wayne
Titel	Successful Aging in a 70-Year-Old Man with Down Syndrome: A Case Study
Quelle	In: Intellectual and Developmental Disabilities, 46 (2008) 3, S.215-228 (14 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1934-9556
DOI	10.1352/2008.46:215-228
Schlagwörter	Alzheimers Disease; Dementia; Down Syndrome; Aging (Individuals); Case Studies; Males; Longitudinal Studies; Age Differences; Genetics; Comparative Analysis; Young Adults; Gerontology + Suchen Sie Ihr Suchwort? Demenz; 'Downs Syndrome; Down''s Syndrome'; Down-Syndrom; Aging; Altern; Case study; Fallstudie; Case Study; Male; Männliches Geschlecht; Longitudinal study; Longitudinal method; Longitudinal methods; Längsschnittuntersuchung; Age; Difference; Age difference; Altersunterschied; Humangenetik; Young adult; Junger Erwachsener; Gerontologie
Abstract	The authors present a case study of a 70-year-old man with Down syndrome ("Mr. C.") who they followed for 16 years and who does not exhibit declines in cognitive or functional capacities indicative of dementia, despite having well-documented, complete trisomy 21. The authors describe the age-associated changes that occurred over 16 years as well as provide detailed information regarding Mr. C.'s health and genetic status. To further emphasize Mr. C.'s successful aging, the authors compared his longitudinal performance profile with that of 2 peers of comparable level of intellectual functioning: 1 similar-aged man with clinical Alzheimer's disease and a younger man who was healthy. The authors present potential explanations for the phenotypic variability observed in individuals with Down syndrome. (As Provided).
Anmerkungen	American Association on Intellectual and Developmental Disabilities. P.O. Box 7065, Lawrence, KS 66044-7065. Tel: 785-843-1235; Fax: 785-843-1274; e-mail: AJMR@allenpress.com; Web site: http://aamr.allenpress.com
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10