Literaturnachweis - Detailanzeige
Autor/in | King, Angela G. |
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Titel | Secondary Structure Switch |
Quelle | In: Journal of Chemical Education, 83 (2006) 1, S.10-14 (5 Seiten)Infoseite zur Zeitschrift
PDF als Volltext |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 0021-9584 |
Schlagwörter | Alzheimers Disease; Neurological Impairments; Structural Analysis (Science); Organic Chemistry; Brain; Diseases |
Abstract | Neurogenerative diseases like Alzheimer's disease and Parkinson's disease involve a transformation between two peptide and protein structures of alpha-helices and beta-sheets, where the peptide backbone can also participate in metal ion binding in addition to histidine residues. However, the complete absence of change in conformation of Coiled Coil upon addition of metal ions reveal the importance of metal complexation by histidine as a trigger mechanism. (Author). |
Anmerkungen | Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail: jchemed@egpp.com; Web site: http://jchemed.chem.wisc.edu/ |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2017/4/10 |