Literaturnachweis - Detailanzeige
| Autor/inn/en | Wentland, Mark P.; Raza, Shaan; Yingtong Gao |
|---|---|
| Titel | 96-Well Plate Colorimetric Assay for K(sub i) Determination of (plusmn)-2-Benzylsuccinic Acid, an Inhibitor of Carboxypeptidase A |
| Quelle | In: Journal of Chemical Education, 81 (2004) 3, S.398 (3 Seiten)Infoseite zur Zeitschrift |
| Sprache | englisch |
| Dokumenttyp | gedruckt; Zeitschriftenaufsatz |
| ISSN | 0021-9584 |
| Schlagwörter | Biochemistry; Science Experiments; Science Instruction; Scientific Methodology; Pharmacology; Molecular Structure |
| Abstract | An appropriate assay to determine the inhibition potency of carboxypeptidase A (CPA) in 96-well format to illustrate how high throughput screening is used in modern drug discovery to identify bioactive molecules is developed. Efforts in developing a colorimetric 96-well plate assay for determination of the K(sub i) for inhibition of CPA by (plusmn)-2-benzylsuccinic acid using Ac-phe-Thiaphe-OH as substrate is reported. (Author). |
| Anmerkungen | Journal of Chemical Education, Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Web site: http://jchemed.chem.wisc.edu/AboutJCE/contact.html. |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2017/4/10 |
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