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Autor/inn/en | Cesare, Victor; Sadarangani, Ishwar; Rollins, Janet; Costello, Dennis |
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Titel | The Synthesis and Isolation of N-Tert-Butyl-2-Phenylsuccinamic Acid and N-Tert-Butyl-3-Phenylsuccinamic Acid: An Undergraduate Organic Chemistry Laboratory Experiment |
Quelle | In: Journal of Chemical Education, 81 (2004) 5, S.713-714 (2 Seiten)Infoseite zur Zeitschrift |
Sprache | englisch |
Dokumenttyp | gedruckt; Zeitschriftenaufsatz |
ISSN | 0021-9584 |
Schlagwörter | Leitfaden; Unterricht; Lehrer; Laboratory Experiments; Organic Chemistry; Science Instruction; Teaching Methods; Science Experiments; Undergraduate Study Lesson concept; Instruction; Unterrichtsentwurf; Unterrichtsprozess; Teacher; Teachers; Lehrerin; Lehrende; Laboratory work; Laborarbeit; Organische Chemie; Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Teaching method; Lehrmethode; Unterrichtsmethode; Grundstudium |
Abstract | The facile, high yielding synthesis of phenylsuccinamic acids is described and one of these syntheses, the reaction of phenylsuccinic anhydride with tert-butylamine, is successfully modified and adapted for use in the second-semester organic chemistry laboratory at St. John's University. Succinamic acids are compounds that contain both the amide and carboxylic acid functionalities and are of interest because succinate-based hydroxamic acids have been shown to have anti cancer activity. (Author). |
Anmerkungen | Journal of Chemical Education, Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Web site: http://jchemed.chem.wisc.edu/AboutJCE/contact.html. |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2017/4/10 |