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Autor/inn/enBilleci, Lucia; Callara, Alejandro Luis; Guiducci, Letizia; Prosperi, Margherita; Morales, Maria Aurora; Calderoni, Sara; Muratori, Filippo; Santocchi, Elisa
TitelA Randomized Controlled Trial into the Effects of Probiotics on Electroencephalography in Preschoolers with Autism
QuelleIn: Autism: The International Journal of Research and Practice, 27 (2023) 1, S.117-132 (16 Seiten)
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ZusatzinformationORCID (Prosperi, Margherita)
Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN1362-3613
DOI10.1177/13623613221082710
SchlagwörterAutism Spectrum Disorders; Preschool Children; Food; Health Education; Brain Hemisphere Functions
AbstractPrevious studies suggest that autism spectrum disorders are characterized by alterations in the microbiota-gut-brain axis. Probiotics may modify the composition and the functionality of the gut microbiota of autism spectrum disorder individuals, with possible cascading effects on brain function. In this study, we analyzed possible brain modifications induced by the administration of probiotics in 46 children with autism spectrum disorder using electroencephalography. A randomized 6-month controlled trial was performed. In subjects treated with probiotics, we observed a decrease of power in frontopolar regions in beta and gamma bands, and increased coherence in the same bands together with a shift in frontal asymmetry, which suggests a modification toward a typical brain activity. Electroencephalography measures were significantly correlated with clinical and biochemical measures. These findings support the importance of further investigations on probiotics' benefits in autism spectrum disorder to better elucidate mechanistic links between probiotics supplementation and changes in brain activity. (As Provided).
AnmerkungenSAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2024/1/01
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