Early Life Antibiotic Exposure and the Subsequent Risk of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis

Autor/inn/en	Yu, Hai-ying; Zhou, Yuan-yue; Pan, Li-ya; Zhang, Xue; Jiang, Hai-yin
Titel	Early Life Antibiotic Exposure and the Subsequent Risk of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis
Quelle	In: Journal of Autism and Developmental Disorders, 52 (2022) 5, S.2236-2246 (11 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-021-05121-6
Schlagwörter	Autism; Pervasive Developmental Disorders; Attention Deficit Hyperactivity Disorder; Drug Use; Correlation; Family Influence; Siblings + Suchen Sie Ihr Suchwort? Autismus; Drug consumption; Substance abuse; Drogenkonsum; Korrelation; Sibling; Geschwister
Abstract	This study was conducted to assess this association between early life antibiotic exposure and the risk of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in later life. The results showed that early life antibiotic exposure was associated with an increased risk of ASD (OR = 1.13, 95% confidence interval (CI): 1.07-1.21) or ADHD (OR = 1.18, 95% CI: 1.1-1.27). However, this association for ASD (OR = 1.04, 95% CI: 0.97-1.11) or ADHD (OR = 0.98, 95% CI: 0.94-1.02) disappeared when data from sibling-matched studies were pooled. The statistically significant association between early life antibiotic exposure and ASD or ADHD in later life can be partially explained by unmeasured genetic and familial confounding factors. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01