Experience Enhances Certainty about Olfactory Stimuli under Bulbar Cholinergic Control

Autor/inn/en	Cho, Christina; Linster, Christiane
Titel	Experience Enhances Certainty about Olfactory Stimuli under Bulbar Cholinergic Control
Quelle	In: Learning & Memory, 27 (2020) 10, S.414-417 (4 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Linster, Christiane)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.051854.120
Schlagwörter	Olfactory Perception; Sensory Integration; Stimuli; Role; Brain Hemisphere Functions; Animal Behavior; Responses; Measurement; Learning Processes; Correlation; Learning Experience + Suchen Sie Ihr Suchwort? Sensorische Integration; Anreizsystem; Rollen; Tierverhalten; Messverfahren; Learning process; Lernprozess; Korrelation; Lernerfahrung
Abstract	We present evidence that experience and cholinergic modulation in an early sensory network interact to improve certainty about olfactory stimuli. The data we present are in agreement with existing theoretical ideas about the functional role of acetylcholine but highlight the importance of early sensory networks in addition to cortical networks. We use a simple behavioral paradigm in mice which allows us to measure certainty about a stimulus via the response amplitude to a condition and novel stimuli. We conclude that additional learning increases certainty and that the slope of this relationship can be modulated by activation of muscarinic cholinergic receptors in the olfactory bulb. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://learnmem.cshlp.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01