An Appraisal of Meta-Analysis Guidelines: How Do They Relate to Safety Outcomes?

Autor/inn/en	Bennetts, Meg; Whalen, Ed; Ahadieh, Sima; Cappelleri, Joseph C.
Titel	An Appraisal of Meta-Analysis Guidelines: How Do They Relate to Safety Outcomes?
Quelle	In: Research Synthesis Methods, 8 (2017) 1, S.64-78 (15 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Bennetts, Meg)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1759-2879
DOI	10.1002/jrsm.1219
Schlagwörter	Meta Analysis; Guidelines; Network Analysis; Safety; Data + Suchen Sie Ihr Suchwort? Meta-analysis; Metaanalyse; Richtlinien; Netzplantechnik; Sicherheit; Daten
Abstract	Although well developed to assess efficacy questions, meta-analyses and, more generally, systematic reviews, have received less attention in application to safety-related questions. As a result, many open questions remain on how best to apply meta-analyses in the safety setting. This appraisal attempts to: (i) summarize the current guidelines for assessing individual studies, systematic reviews, and network meta-analyses; (ii) describe several publications on safety meta-analytic approaches; and (iii) present some of the questions and issues that arise with safety data. A number of gaps in the current quality guidelines are identified along with issues to consider when performing a safety meta-analysis. While some work is ongoing to provide guidance to improve the quality of safety meta-analyses, this review emphasizes the critical need for better reporting and increased transparency regarding safety data in the systematic review guidelines. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01