Literaturnachweis - Detailanzeige
Autor/inn/en | Schafer, Adam G.; Yezierski, Ellen J.; Hartley, C. Scott |
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Titel | Understanding Thermodynamic Control in Covalent Self-Assembly: A Mixed Synthetic-Computational Experiment for the Undergraduate Organic-Chemistry Laboratory |
Quelle | In: Journal of Chemical Education, 96 (2019) 6, S.1230-1235 (6 Seiten)Infoseite zur Zeitschrift
PDF als Volltext |
Zusatzinformation | ORCID (Schafer, Adam G.) ORCID (Yezierski, Ellen J.) ORCID (Hartley, C. Scott) |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 0021-9584 |
Schlagwörter | Undergraduate Students; Thermodynamics; Laboratory Experiments; Comparative Analysis; Organic Chemistry; Computer Assisted Instruction; Hands on Science; Inquiry; Teaching Methods |
Abstract | A laboratory experiment was developed that connects the interpretation of computer-generated models to the self-assembly of macrocycles. Students compare the reactions of terephthalaldehyde and isophthalaldehyde by reacting each with (R,R)-(-)-1,2-diaminocyclohexane. These isomeric systems serve as the foundation for a discussion about the impact of entropy and enthalpy on macrocycle formation. This experiment requires students to use multiple data sources to develop evidence-based explanations about the impact of the startingmaterial geometry on macrocyclization. Results from laboratory implementation indicate that a majority of students were able to successfully demonstrate competency of the learning goals. (As Provided). |
Anmerkungen | Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2020/1/01 |