Symptoms of Autism Spectrum Disorder (ASD) in Individuals with Mucopolysaccharide Disease Type III (Sanfilippo Syndrome): A Systematic Review

Autor/inn/en	Wolfenden, C.; Wittkowski, A.; Hare, D. J.
Titel	Symptoms of Autism Spectrum Disorder (ASD) in Individuals with Mucopolysaccharide Disease Type III (Sanfilippo Syndrome): A Systematic Review
Quelle	In: Journal of Autism and Developmental Disorders, 47 (2017) 11, S.3620-3633 (14 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-017-3262-6
Schlagwörter	Autism; Pervasive Developmental Disorders; Genetic Disorders; Symptoms (Individual Disorders); Comorbidity; Literature Reviews; Speech Impairments; Language Impairments; Communication Problems; Behavior Disorders; Interests; Clinical Diagnosis; Observation; Diagnostic Tests; Child Development; Infants; Cognitive Ability; Intelligence Tests; Interpersonal Competence; Personality Measures; Autism Diagnostic Observation Schedule; Bayley Scales of Infant Development; Stanford Binet Intelligence Scale; Vineland Social Maturity Scale + Suchen Sie Ihr Suchwort? Autismus; Psychiatrische Symptomatik; Speech impairment; Speech handicap; Speech handicaps; Language handicps; Language impairments; Sprachbehinderung; Speech disorder; Speech disorders; Speech disabilities; Speech disability; Speech impairments; Language handicaps; Kommunikationsbarriere; Bildungsinteresse; Beobachtung; Diagnostic test; Diagnostischer Test; Kindesentwicklung; Infant; Toddler; Toddlers; Kleinkind; Denkfähigkeit; Intelligence test; Intelligenztest; Interpersonale Kompetenz
Abstract	The prevalence of autism spectrum disorder (ASD) in many genetic disorders is well documented but not as yet in Mucopolysaccharidosis type III (MPS III). MPS III is a recessively inherited metabolic disorder and evidence suggests that symptoms of ASD present in MPS III. This systematic review examined the extant literature on the symptoms of ASD in MPS III and quality assessed a total of 16 studies. Results indicated that difficulties within speech, language and communication consistent with ASD were present in MPS III, whilst repetitive and restricted behaviours and interests were less widely reported. The presence of ASD-like symptoms can result in late diagnosis or misdiagnosis of MPS III and prevent opportunities for genetic counselling and the provision of treatments. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01