Ideal Cardiovascular Health and Incident Cardiovascular Disease Among Adults: A Systematic Review and Meta-analysis.

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Autor/Urheber	"Ramírez-Vélez, Robinson; Saavedra, José M; Lobelo, Felipe; Celis-Morales, Carlos A; del Pozo-Cruz, Borja; García-Hermoso, Antonio"
Institution	Elsevier Ltd
Titel	Ideal Cardiovascular Health and Incident Cardiovascular Disease Among Adults: A Systematic Review and Meta-analysis.
Quelle	In: 256196; instname:Universidad del Rosario ; reponame:Repositorio Institucional EdocUR(2018) PDF als Volltext kostenfreie Datei
Sprache	englisch
Dokumenttyp	online; Zeitschriftenaufsatz
DOI	10.1016/j.mayocp.2018.05.035
Schlagwörter	Adult; Age; Aged; Article; Cardiovascular disease; Cardiovascular risk; Cohort analysis; Hazard ratio; Health; Heart rate; High risk population; Human; Incidence; Major clinical study; Systematic review; Cardiovascular function; Cardiovascular system; Female; Health status; Male; Meta analysis; Proportional hazards model; Prospective study; Age factors; Cardiovascular diseases; Cardiovascular physiological phenomena; Humans; Proportional hazards models; Prospective studies
Abstract	"Objective: To investigate the association between ideal cardiovascular health (CVH) metrics and incident cardiovascular disease (CVD) by conducting a systematic review and meta-analysis of prospective cohort studies. Methods: The MEDLINE, EMBASE, and CINAHL databases were searched from January 1, 2010, through July 31, 2017, for studies that met the following criteria: (1) prospective studies conducted in adults, (2) with outcome data on CVD incidence and (3) a measure of ideal CVH metrics. Results: Twelve studies (210,443 adults) were included in this analysis. Compared with adults who met 0 to 2 of the ideal CVH metrics (high-risk individuals), a significantly lower hazard for CVD incidence was observed in those who had 3 to 4 points for the ideal CVH metrics (hazard ratio [HR]=0.53; 95% CI, 0.47-0.59) and 5 to 7 points (HR=0.28; 95% CI, 0.23-0.33). Weaker associations were observed in studies with older individuals, suggesting that there is a positive relationship between age and HR. Conclusion: Although meeting 5 to 7 metrics is associated with the lowest hazard for CVD incidence, meeting 3 to 4 metrics still offers an important protective effect for CVD. Therefore, a realistic goal in the general population in the short term could be to promote at least an intermediate ideal CVH profile (3 to 4 metrics). © 2018 Mayo Foundation for Medical Education and Research"
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