Literaturnachweis - Detailanzeige
Autor/inn/en | Halperin, Jeffrey M.; Kalmar, Jessica H.; Schulz, Kurt P.; Marks, David J.; Sharma, Vanshdeep; Newcorn, Jeffrey H. |
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Titel | Elevated Childhood Serotonergic Function Protects against Adolescent Aggression in Disruptive Boys |
Quelle | In: Journal of the American Academy of Child & Adolescent Psychiatry, 45 (2006) 7, S.833-840 (8 Seiten)
PDF als Volltext |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 0890-8567 |
DOI | 10.1097/01.chi.0000220855.79144.ae |
Schlagwörter | Aggression; Behavior Disorders; Children; Males; Drug Therapy; Longitudinal Studies; Metabolism; Adolescents; Antisocial Behavior; At Risk Persons |
Abstract | Objective: This longitudinal study examined whether responsiveness of the neurotransmitter serotonin (5-HT) in childhood predicts adolescent aggression. Method: Boys (N = 33) with disruptive behavior disorders who received assessments of central 5-HT function via the prolactin response to fenfluramine between 1990 and 1994 when they were 7 to 11 years old were re-evaluated clinically on average 6.7 years later. Results: After accounting for baseline aggression, early 5-HT function accounted for a significant proportion of variance in adolescent aggression. This prospective relationship of childhood 5-HT function with adolescent aggression (r = -0.71) and antisocial behavior (r = -0.59) was found primarily in adolescents who were aggressive during childhood. Irrespective of childhood aggression, no child with high 5-HT function was particularly aggressive at follow-up. Conclusions: Low childhood 5-HT function appears important, but not sufficient, for the emergence of adolescent aggression. However, early high 5-HT function may protect against adolescent violence and aggression. (Contains 2 figures and 2 tables.) (As Provided). |
Anmerkungen | Elsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2017/4/10 |