Intra-Amygdala ZIP Injections Impair the Memory of Learned Active Avoidance Responses and Attenuate Conditioned Taste-Aversion Acquisition in Rats

Autor/inn/en	Gamiz, Fernando; Gallo, Milagros
Titel	Intra-Amygdala ZIP Injections Impair the Memory of Learned Active Avoidance Responses and Attenuate Conditioned Taste-Aversion Acquisition in Rats
Quelle	In: Learning & Memory, 18 (2011) 8, S.529-533 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.2253311
Schlagwörter	Stimuli; Control Groups; Memory; Animals; Inhibition; Responses; Conditioning; Retention (Psychology); Brain Hemisphere Functions; Comparative Analysis; Learning Processes + Suchen Sie Ihr Suchwort? Anreizsystem; Gedächtnis; Animal; Tier; Tiere; Hemmung; Merkfähigkeit; Learning process; Lernprozess
Abstract	We have investigated the effect of protein kinase Mzeta (PKM[zeta]) inhibition in the basolateral amygdala (BLA) upon the retention of a nonspatial learned active avoidance response and conditioned taste-aversion (CTA) acquisition in rats. ZIP (10 nmol/[mu]L) injected into the BLA 24 h after training impaired retention of a learned avoidance-jumping response assessed 7 d later when compared with control groups injected with scrambled-ZIP. Nevertheless, a retraining session applied 24 h later indicated no differences between the groups. Additionally, a similar ZIP injection into the BLA during the conditioned stimulus-unconditioned stimulus (CS-US) interval attenuated CTA acquisition. These findings support the BLA PKM[zeta] role in various forms of memory. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10