Transient Relay Function of Midline Thalamic Nuclei during Long-Term Memory Consolidation in Humans

Autor/inn/en	Thielen, Jan-Willem; Takashima, Atsuko; Rutters, Femke; Tendolkar, Indira; Fernández, Guillén
Titel	Transient Relay Function of Midline Thalamic Nuclei during Long-Term Memory Consolidation in Humans
Quelle	In: Learning & Memory, 22 (2015) 10, S.527-531 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.038372.115
Schlagwörter	Hypothesis Testing; Memory; Diagnostic Tests; Brain Hemisphere Functions; Cognitive Processes; Short Term Memory; Long Term Memory + Suchen Sie Ihr Suchwort? Hypothesenprüfung; Hypothesentest; Gedächtnis; Diagnostic test; Diagnostischer Test; Cognitive process; Kognitiver Prozess; Kurzzeitgedächtnis; Langzeitgedächtnis
Abstract	To test the hypothesis that thalamic midline nuclei play a transient role in memory consolidation, we reanalyzed a prospective functional MRI study, contrasting recent and progressively more remote memory retrieval. We revealed a transient thalamic connectivity increase with the hippocampus, the medial prefrontal cortex (mPFC), and a parahippocampal area, which decreased with time. In turn, mPFC-parahippocampal connectivity increased progressively. These findings support a model in which thalamic midline nuclei serve as a hub linking hippocampus, mPFC, and posterior representational areas during memory retrieval at an early (2 h) stage of consolidation, extending classical systems consolidation models by attributing a transient role to midline thalamic nuclei. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01