Extended Treatment with Bupropion SR for Cigarette Smoking Cessation

Autor/inn/en	Killen, Joel D.; Fortmann, Stephen P.; Murphy, Greer M.; Hayward, Chris; Arredondo, Christina; Cromp, DeAnn; Celio, Maria; Abe, Laurie; Wang, Yun; Schatzberg, Alan F.
Titel	Extended Treatment with Bupropion SR for Cigarette Smoking Cessation
Quelle	In: Journal of Consulting and Clinical Psychology, 74 (2006) 2, S.286-294 (9 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0022-006X
Schlagwörter	Smoking; Adults; Prevention; Responses; Gender Differences; Comparative Analysis; Outcomes of Treatment; Program Effectiveness; Health Promotion + Suchen Sie Ihr Suchwort? Rauchen; Prävention; Vorbeugung; Geschlechterkonflikt; Gesundheitsfürsorge; Gesundheitshilfe; Reihenuntersuchung
Abstract	The authors present results of a randomized clinical trial of the efficacy of extended treatment with bupropion SR in producing longer term cigarette smoking cessation. Adult smokers (N = 362) received open-label treatment (11 weeks) that combined relapse prevention training, bupropion SR, and nicotine patch followed by extended treatment (14 weeks) with bupropion SR or matching placebo. Abstinence percentages were relatively high (week 11: 52%; week 25: bupropion, 42%; placebo, 38%; week 52: bupropion, 33%; placebo, 34%), but bupropion SR did not surpass placebo. Gender and baseline craving level were identified as significant, independent moderators of treatment response. Men were more likely to abstain than women (week 11: 59% vs. 43%, p = 0.001; week 25: 48% vs. 31%, p = 0.001; week 52: 39% vs. 27%, p = 0.01). Because most smokers suffer relapse with any current cessation treatment, the comparatively high abstinence percentages achieved in this trial are of interest. (Author).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10